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Recognize the symptoms of
anaphylaxis and know
how to respond.

Anaphylaxis is an emergency medical condition that can quickly progress after initial symptom onset. Learn more about its prevalence, prevention guidelines, as well as why and how to respond.

Just how common is it?

In the United States, the number of anaphylactic events has risen in recent years, and it is estimated 6 million children have food allergies.2-5

Research shows hospital admissions for food-related anaphylaxis have increased in the last 20 years and has more than doubled in patients 0-18 years of age between 2000-2009. Other data show food-related allergic emergencies send someone to the hospital on average every 3 minutes in the US.2,6-8

Get some food for thought

Risk factors for anaphylaxis

Anaphylaxis can occur when susceptible individuals are exposed to certain allergens. Common allergens include food, insect stings and bites, medications, and latex.9,10

People with asthma and/or other allergies who have experienced severe allergic reactions are more likely to experience anaphylaxis—even if an offending allergen didn’t cause anaphylaxis in the past.9

Early symptoms of anaphylaxis can be mild, but quickly progress. These include9,11:

Because anaphylaxis is a life-threatening allergic reaction, recognizing these symptoms, and their triggers, is critical.9

Have an Anaphylaxis Emergency Plan

Medical practice guidelines address both anaphylaxis prevention and the importance of using epinephrine9:

Work with your doctor to customize an Anaphylaxis Emergency Plan. There are several examples available online, including
the following from Food Allergy Research & Education (FARE).

Start your plan

In the United States, >1/2 of fatal food allergic reactions occur outside the home and, when they occur, people are not always aware their food contained an allergen.12-14

When anaphylaxis occurs,
epinephrine should be administered immediately15

Ticking clock

Anaphylactic reactions should be treated immediately with an injection of epinephrine.15 Epinephrine auto-injectors are available by prescription and should be kept nearby at all times.

Anaphylactic reactions can be unpredictable,9,12 therefore knowing how to use—and being ready to use—an epinephrine auto-injector could help save a life.

A Canadian study of 965 cases of anaphylaxis (median age 5.8 years) showed only 51% of patients who had an epinephrine auto-injector used it before arrival to the emergency department.16

Myths, facts,
and food allergies.

Get the facts

When it comes to life-threatening allergies, there are a lot of misconceptions out there. But it’s important to separate fact from fiction, and deal with the realities of anaphylaxis, who it affects, and how often it really occurs.


AUVI-Q® (epinephrine injection, USP) is a prescription medicine used to treat life-threatening allergic reactions, including anaphylaxis, in people who are at risk for or have a history of serious allergic reactions.

Important Safety Information

AUVI-Q is for immediate self (or caregiver) administration and does not take the place of emergency medical care. Seek immediate medical treatment after using AUVI-Q. Each AUVI-Q contains a single dose of epinephrine. AUVI-Q should only be injected into your outer thigh, through clothing if necessary. If you inject a young child or infant with AUVI-Q, hold their leg firmly in place before and during the injection to prevent injuries. Do not inject AUVI-Q into any other part of your body, such as into veins, buttocks, fingers, toes, hands, or feet. If this occurs, seek immediate medical treatment and make sure to inform the healthcare provider of the location of the accidental injection. Only a healthcare provider should give additional doses of epinephrine if more than two doses are necessary for a single allergic emergency.

Rarely, patients who use AUVI-Q may develop infections at the injection site within a few days of an injection. Some of these infections can be serious. Call your healthcare provider right away if you have any of the following symptoms at an injection site: redness that does not go away, swelling, tenderness, or the area feels warm to the touch.

If you have certain medical conditions, or take certain medicines, your condition may get worse or you may have more or longer lasting side effects when you use AUVI-Q. Be sure to tell your healthcare provider about all the medicines you take, especially medicines for asthma. Also tell your healthcare provider about all of your medical conditions, especially if you have asthma, a history of depression, thyroid problems, Parkinson’s disease, diabetes, heart problems or high blood pressure, have any other medical conditions, are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed. Epinephrine should be used with caution if you have heart disease or are taking certain medicines that can cause heart-related (cardiac) symptoms.

Common side effects include fast, irregular or ‘pounding’ heartbeat, sweating, shakiness, headache, paleness, feelings of over excitement, nervousness, or anxiety, weakness, dizziness, nausea and vomiting, or breathing problems. These side effects usually go away quickly, especially if you rest. Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088.